N-[(3S)-5-oxo-3-oxolanyl]-N-(phenylmethyl)carbamate

N-[(3S)-5-oxo-3-oxolanyl]-N-(phenylmethyl)carbamate - Names and Identifiers

Name	benzyl (S)-(-)-tetrahydro-5-oxo-3-furanyl-carbama
Synonyms	Cbz-S-3-Amino-γ-butyrolactone (S)-Benzyl-5-oxo-tetrahydro-furan-3-ylcarbamate benzyl [(3S)-5-oxotetrahydrofuran-3-yl]carbamate (S)-3-[(benzyloxycarbonyl)amino]-g-butyrolactone benzyl (S)-(-)-tetrahydro-5-oxo-3-furanyl-carbama Benzyl (S)-(?-tetrahydro-5-oxo-3-furanylcarbamate Benzyl (D)-(-)-tetrahydro-5-oxo-3-furanylcarbamate BENZYL (S)-(-)-TETRAHYDRO-5-OXO-3-FURANYLCARBAMATE N-[(3S)-5-oxo-3-oxolanyl]-N-(phenylmethyl)carbamate (S)-(Tetrahydro-5-oxo-3-furanyl)carbamic acid phenylmethyl ester Carbamic acid, [(3S)-tetrahydro-5-oxo-3-furanyl]-, phenylmethyl ester (9CI)
CAS	87219-29-2
InChI	InChI=1/C12H13NO4/c14-11-6-10(8-16-11)13-12(15)17-7-9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H,13,15)/t10-/m0/s1

N-[(3S)-5-oxo-3-oxolanyl]-N-(phenylmethyl)carbamate - Physico-chemical Properties

Molecular Formula	C12H13NO4
Molar Mass	235.24
Density	1.27
Melting Point	103-105 °C (lit.)
Boling Point	466.1±44.0 °C(Predicted)
Flash Point	235.681°C
Solubility	soluble in Chloroform
Vapor Presure	0mmHg at 25°C
Appearance	White powder
Color	White
pKa	10.87±0.20(Predicted)
Storage Condition	2-8°C
Refractive Index	1.561
MDL	MFCD00216569
Physical and Chemical Properties	Melting Point: 103-105°C(lit.) density: 1.27

N-[(3S)-5-oxo-3-oxolanyl]-N-(phenylmethyl)carbamate - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	43 - May cause sensitization by skin contact
Safety Description	S36/37 - Wear suitable protective clothing and gloves. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29321900

N-[(3S)-5-oxo-3-oxolanyl]-N-(phenylmethyl)carbamate - Introduction

benzyl (S)-(-)-tetrahydro-5-oxo-3-furanyl-carbama is a compound whose chemical formula is C16H17NO4.

Properties: benzyl (S)-(-)-tetrahydro-5-oxo-3-furanyl-carbama is a colorless solid, soluble in ethanol and chloroform, with a special smell.

Purpose: Benzyl (S)-(-)-tetrahydro-5-oxo-3-furanyl-carbama is commonly used as a chiral intermediate and plays a catalytic role in organic synthesis, especially in the preparation of chiral drugs and the synthesis of natural products.

preparation method: benzyl (S)-(-)-tetrahydro-5-oxo-3-furanyl-carbama has many preparation methods. one common method is to react (S)-2-hydroxy -4-aminobutyric acid with benzaldehyde to generate the corresponding alcohol, and then generate the target product through esterification reaction.

Safety Information: There are no clear reports of toxicity and danger of benzyl (S)-(-)-tetrahydro-5-oxo-3-furanyl-carbama. However, as a chemical substance, it should follow appropriate laboratory practices, avoid inhalation and direct contact with skin and eyes, and use personal protective equipment when necessary to ensure safe handling.

Last Update：2024-04-09 20:45:29